CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USE

Smart overview of the Invention

The patent application introduces methods for synthesizing various cannabinoids, such as cannabidiol (CBD) and its analogs, through stereospecific, efficient, and cost-effective processes. These methods avoid the generation of psychoactive byproducts like THC. The synthesis begins with phloroglucinol or its analogs, enabling the production of cannabinoids and their synthetic precursors. The approach is designed to be adaptable, allowing for the creation of a wide range of cannabinoids and their formulations.

Technical Field

This invention pertains to the chemical synthesis of cannabinoids, focusing on methods that produce CBD and its analogs. The synthesized compounds have applications in medicine, therapeutics, and pharmaceutical manufacturing. The invention also covers the production of reactants used in these syntheses and the utilization of the synthesized cannabinoids for therapeutic purposes.

Background

Cannabinoids, particularly CBD, have gained attention for their therapeutic potential. CBD is known for its anti-inflammatory, neuroprotective, and anti-oxidant properties, with applications in treating pain, anxiety, and other conditions. Traditionally, cannabinoids are extracted from Cannabis sativa, but this process is complex and challenging due to the similarities among phytocannabinoids. Thus, chemical synthesis offers a reliable alternative for producing high-quality cannabinoids without contaminants.

Previous Syntheses Challenges

Earlier methods for synthesizing CBD, such as those developed by Mechoulam and Petrzilka, faced challenges like high costs, poor regioselectivity, and low yields. These methods often resulted in a mixture of products, complicating the isolation of the desired cannabinoid. Improvements have been made, but an ideal synthesis would streamline the process, reduce byproducts, and be economically viable.

Summary of the Invention

The invention addresses the need for an improved synthesis method by offering a stereoselective approach that minimizes byproducts and simplifies product separation. It allows for the production of cannabinoids in high yields under mild conditions. The method can be performed as a "one pot" reaction, enhancing efficiency and cost-effectiveness. Additionally, the invention includes novel cannabinoids and pharmaceutical formulations, as well as methods for their therapeutic use, providing a comprehensive solution to cannabinoid synthesis and application.